The Research Networking Programme "BIOLUPUS" ended its activities in June 2014 and is in its final review phase.
Systemic lupus erythematosus (SLE) is a chronic inflammatory disease considered a prototype of autoimmune disease and inflammation. Without effective therapy SLE causes serious morbidity in about 1 in 2000 women aged between 20 and 50 years of age and considerable socioeconomic burden on European society.
The BIOLUPUS group has as long-term objective to apply genomics, proteomics and the use of translational databases to the identification of biomarkers of clinical utility. Thirty-five participants from 13 European countries are involved in this enterprise involving clinicians, immunologists and geneticists.
The network will serve as a basis for the creation of a database with clinical, environmental and demographic information that can be used for genetics studies as well as clinical trials of new drugs.
5 years, from June 2009 to June 2014 (07-RNP-083)