Confdetail207 : European Science Foundation

ESF-Wellcome Trust Conference

HUMANISING MODEL ORGANISMS TO UNDERSTAND THE PATHOGENESIS OF HUMAN DISEASE

Chaired by

CHAIR:

RolandWolfE-Mail: University of DundeeBiomedical Research CentreDundeeUnited Kingdom

http://www.dundee.ac.uk/biomedres/

CO-CHAIRS:

SteveBrownE-Mail: Medical Research CouncilMammalian Genetics UnitHarwellUnited Kingdom

RudiBallingE-Mail: Helmholtz-Zentrum für InfektionsforschungBraunschweigGermany

NicholasHastieE-Mail: Medical Research CouncilWestern General HospitalHuman Genetics UnitComparative and Developmental Genetics SectionEdinburghUnited Kingdom

NadiaRosenthalE-Mail: EMBL MonterotondoEMBL Mouse Biology UnitMonterotondo ScaloItaly

Dates

1-3 May 2007

Location

Wellcome Trust Genome Campus, Hinxton, UK
The Wellcome Trust Genome Campus is located close to Cambridge and London Stansted airport. Participants will be requested to make their own way to/from the conference center on arrival and departure days.

Final Programme & List of Accepted Participants

Advances in genomics and molecular genetics have made an enormous contribution to understanding the pathogenesis of human disease. Exploitation of this knowledge has opened up new avenues of research where the genes and pathways altered in human disease can be reproduced in animal “humanised” models. These systems have enormous potential not only in the development of new strategies for disease prevention but also for the validation of new drug targets and for drug efficacy screening. These models also provide an experimental approach to understanding the relative role of environment versus genetic factors in disease aetiology – a research area that is almost intractable with other current experimental models. In addition, the genes that have evolved to protect animals from the environment can exhibit marked species differences in their functions, level of expression and regulation. This can often lead to great difficulty in extrapolating drug safety data obtained as part of drug development in animals to man. An approach to circumvent some of these problems is the generation of models that have been “humanised” for these metabolic pathways. It is the aim of this ESF-WT Conference to report and discuss some of the outstanding advances that have recently been made in modelling human disease and foreign compound metabolism and how these models can be applied to disease prevention and to the development of new drug therapies.

Final Programme PDF (59 KB) Last updated 27-April-2007
List of Invited Speakers & Accepted Participants

Abstracts, Posters & Short Oral Contributions

There will be no short talks other than those listed in the programme. All abstracts are accepted as posters. Posters will be displayed for the whole duration of the conference.

Posters may be fixed with velcro or pins (available on site) but no blu tack or adhesive tape. Maximum poster size is 100 x 100 cm. There are 2 formats: landscape (190 x 110 cm) and portrait (110 x 170 cm). Please use letters and drawings that can be read from approximately 100 cm distance.

Registration

All participants (including invited speakers and chairs) are expected to confirm their attendance by sending an email to Ms. Chiara Orefice.
Closing date for registration: 25 April 2007

Conference Fees

Fees	What the fees cover
Student Fees
GBP 365 (approximately EUR 537)	conference, meals and single room
GBP 315 (approximately EUR 464)	conference, meals and twin room
GBP 237 (approximately EUR 349)	non-resident: conference, meals (no room)
Academic Fees
GBP 465 (approximately EUR 685)	conference, meals and single room
GBP 415 (approximately EUR 611)	conference, meals and twin room
GBP 337 (approximately EUR 496)	non-resident: conference, meals (no room)
Commercial Fees
GBP 565 (approximately EUR 832)	conference, meals and single room
GBP 515 (approximately EUR 758)	conference, meals and twin room
GBP 437 (approximately EUR 643)	non-resident: conference, meals (no room)

The conference fee must be paid directly to the Wellcome Trust Conference Center, once you have been informed of your acceptance to the meeting. Please contact Ms. Patricia van der Valk, Conference Officer, Wellcome Trust. No payment will be handled by the ESF Conferences Unit.
Closing date for fee payment: 25 April 2007

Practical Information Guide

Detailed information on all practical aspects of the conference (access to site, registration & fee payments, accommodation, travel reimbursements...) is available from the Practical Information Guide. Please read it fully and carefully...

Practical Information Guide PDF (92 KB)