ESF-EMBO Symposium
B Cells and Protection: Back to basics
18-23 April 2010 - Hotel Eden Roc, Sant Feliu de Guixols, Spain
| SUNDAY 18 April |
Late afternoon /early evening Registration at the ESF-RC desk
19.00 Welcome Drink
20.00 Supper
| MONDAY 19 April |
08.45-09.00 Conference Opening
Chair: Rita Carsetti
ESF Rapporteur: Lars Kristiansen, ESF, FR
SESSION 1: The host microbe relationship: a long-standing armed peace
Chair: Rita Carsetti, Research Center, Bambino Gesu Children's Hospital, IT
09.00-09.45: François Leulier, Institut de Biologie du Développement de Marseille Luminy, FR
The control of host-microbes mutualism in absence of B-cells: the Fly case
09.45-10.30: Paul Kubes, University of Calgary, CA
Host- bacteria encounter in the blood vessels
10.30-11.00: Coffee break
11.00-11.45: Hana Kozakova, Inst. of Microbiology, ASCR, CZ
The role of gut microbiota in mucosal tolerance induction: experimental allergy model
11.45-12.30: Andrew Macpherson, McMaster University, CA
Role of microbes shaping the innate and adaptive immune response
12.30: Lunch
16.00-16.30: Coffee Break
SESSION 2:
Chair: Andrew Macpherson, McMaster University, CA
16.30-17.15: Maria Rescigno, European Institute of Oncology, IT
Dendritic cells in the intestine
17.15-18.00: Nils Lycke, Göteborg University, SE
Regulation of innate and adaptive immunity at mucosal membranes
19.00: Dinner
20.30-21.15: Martin Bachmann, Cytos Biotechnology AG, CH
Nanoparticles targeting dendritic cells
21.15 - 22.00: Poster Session
| TUESDAY 20 April |
SESSION 3: B cell diversity: “B” different
Chair: Deborah Dunn-Walters, Kings College London School of Medicine, UK
09.00-09.45: Hedda Wardemann, Max Planck Institute for Infection Biology, DE
Diversity and selection of the B cell repertoire
09.45-10.30: Nicolaas A. Bos, University of Groningen, NL
The site specificity of the IgA repertoire
10.30-11.00: Coffee break - GROUP PHOTO
11.00-11.45: Jo Spencer, Kings College London School of Medicine, UK
Generation of diversity in mucosal immunoglobulin
11.45-12.30: Deborah Dunn-Walters, Kings College London School of Medicine, UK
B cell repertoire and ageing
12.30: Lunch
15.45-16.15: Coffee Break
16.15-17.00: Michael Ehrenstein, University College London, UK
Secreted IgM as regulator of autoimmune responses
SESSION 4: B cell development and function: the regulatory universe
Chair: Yehudit Bergman, The Hebrew University Hadassah Medical School, IL
17.00-17.45: Mikael Sigvardsson, Linköping University, SE
Molecular regulation of B-lymphocyte Commitment
17.45-18.30: Yehudit Bergman, The Hebrew University Hadassah Medical School, IL
Epigenetics of B-cell development
19.00: Dinner
20.00-21.30: Poster Session
| WEDNESDAY 21 April |
SESSION 5: B cell development and function: the art of integrating signals
Chair: Almudena R. Ramiro, Spanish National Cancer Research Center, ES
09.00-09.45: Almudena R. Ramiro, Spanish National Cancer Research Center, ES
MicroRNA and the regulation of AID
09.45-10.30: Martin Turner, The Babraham Institute, UK
Regulating B cell development and activation via RNA binding proteins
10.30-11.00: Coffee break
11.00-11.30: Lill Mårtensson-Bopp, The Babraham Institute, UK
Signalling in pre-B cells
11.30-12.15: Andrew Bowie, Trinity College, IE
Insights into innate immune signalling from viral evasion studies
12.15-13.00: Francesca Chiodi, Karolinska Institutet, SE
Dysfunctional B cells in HIV-1 infection
13.00: Lunch
Afternoon: Half Day Excursion
19.00: Dinner
Short Oral Presentations
Chair: Maria Manuela Rosado, Bambino Gesù Children's Hospital, IT
20.30-20.45: Jenny Hansson, Nestlé Research Center, CH
Effects of early life colonization on B cells ontogeny and function
20.45-21.00: Yang Zhang, University of Birmingham, UK
A model for affinity dependent selection of germinal centre B cells
21.00-21.15: Nancy So, University of Toronto, CA
Vigorous response of human Innate-like IgM memory B cells upon infection by pathogenic Neisseria gonorrhoeae
21.15-21.30: Mats Bemark, University of Gothenburg, SE
Late transitional cells a novel immature human B cell subset differentiated from conventional transitional cells through Cd45RB glycosylation
21.30-21.45: Maria Teresa Bertilaccio, San Raffaele Hospital, IT
Role of Toll-like receptors in chronic lymphocytic leukaemia pathobiology
21.45-22.00: Agata Magdalena Wasik, Karolinska Institutet, SE
The influence of the endocannabinoid system on mTOR pathway in mantle cell lymphoma
| THURSDAY 22 April |
SESSION 6: New technologies for old problems
Chair: Mark Throsby, Merus, NL
09.00-09.45: Mark Throsby, Merus, NL
Development and applications of human therapeutic antibodies in infectious disease
09.45-10.30: Anne des Rieux, Université Catholique de Louvain, BE
Transport of nanoparticles to M cells for oral vaccination
10.30-11.00: Coffee break
11.00-11.45: Maria Angeles Munoz-Fernandez, Hospital General Universitario Gregorio Marañón, ES
New non-viral vectors for siRNA Delivery to inhibit HIV replication
11.45: Poster Session
13.00: Lunch
SESSION 7: When things go wrong: tumors and diseases
Chair: Freda Stevenson, Southampton University Trust, UK
15.30-16.15: Freda Stevenson, Southampton University Trust, UK
A potential life support for human B-cell tumors via interaction between modified surface Ig and lectins of innate immunity
16.15-17.00: Michael Cancro, University of Pennsylvania School of Medicine, US
Roles for BLyS family members in establishing and maintaining humoral immunity
17.00-17.30: Coffee break
17.30-18.15: Jayakumar Poovassery, University of Iowa City, US
B cells and TLRs
18.15-19.00: Hiepe Falk, University of Berlin, DE
Long lived plasma cells and autoimmunity
19.30: Before dinner cocktail
20.00: Conference Dinner
| FRIDAY 23 April |
Breakfast and departure
Abstracts, Posters & Short Oral Presentations
There will be no short oral presentations other than those listed in the programme (10min for the presentation + 5min for discussion).
All abstracts are accepted for poster presentation.
Participants selected for short oral presentation may also bring a poster if they wish. If this is the case, please inform Ms. Jean Kelly to be included in the Poster List.
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Partnership
This conference is organised by the European Science Foundation (ESF) in partnership with the European Molecular Biology Organization (EMBO).
With Support from
