ESF-EMBO Symposium
Emergent Properties of the Cytoskeleton: Molecules to Cells
3-8 October 2010
Final Programme
| Sunday 3 October | |
| 17:00 - 19:00 | Registration at ESF Desk |
| 19:00 | Welcome Drink |
| 19:30 | Dinner |
| Monday 4 October | |
|---|---|
| Welcome Address | |
| 08:30 - 09:00 | Michelle Peckham University of Leeds, UK |
| Session 1: Myosin Structure and Function | |
| 09:00 - 09:30 | Michelle Peckham University of Leeds, UK Diversity in the myosin superfamily |
| 09:30 - 10:00 | Anne Houdusse - Institut Curie, FR How myosin VI moves - answers from structural studies of this reverse motor |
| 10:00 - 10:15 | Jim Sellers - NIH, US Regulation of Drosophila myosin-7a by a binding partner (short talk) |
| 10:15 - 10:30 | Margaret Titus - University of Minnesota, US Chemotactic signalling requires a MyTH/FERM myosin (short talk) |
| 10:30 - 11:00 | Coffee break |
| 11:00 - 11:30 | Claudia Veigel - University of Munich, DE How single myosin motors work under load |
| 11:30 - 12:00 | Justin Molloy - NIMR, UK How actin and myosin are guided by weak forces |
| 12:00 - 12:15 | Dan Mulvihill - University of Kent, UK The recruitment of acetylated and unacetylated tropomyosin to distinct actin polymers permits the discrete regulation of specific myosins in fission yeast (short talk) |
| 12:15 - 12:30 | Matthew Lord - University of Vermont, US Differential regulation of fission yeast myosins via changes in the actin track (short talk) |
| 12:30 | Lunch |
| Session 2: Actin Dynamics and Organisation I | |
| 15:30 - 16:00 | Coffee Break |
| 16:00 - 16:30 | Marie-France Carlier - CNRS, FR Actin Dynamics |
| 16:30 - 16:45 | Jonathan Terman - University of Texas, US |
| 16:45 - 17:00 | Thomas Iskratsch - King's College London, UK |
| 17:00 - 17:30 | Jan Faix - University of Hannover, DE Cofilin and fascin cooperate in the disassembly of filopodia |
| 17:30 - 17:45 | Jennifer Gallop - Harvard Medical School, US Self-assembly of filopodia-like structures on supported lipid bilayers (short talk) |
| 17:45 - 18:00 | Metello Innocenti - Netherlands Cancer Institute, NL Role of mDia2 in filopodium formation as revealed by biochemistry (short talk) |
| 18:00 - 18:15 | Sawako Yamashiro - Scripps Research Institute, US Mammalian tropomodulins nucleate actin polymerization via their actin monomer-binding and filament pointed end-capping activities (short talk) |
| 18:15 - 18:30 | Peter Gunning - University of New South Wales, AU Tropomyosin Tn5NM1/2 regulates cell proliferation (short talk) |
| 19:00 | Dinner |
| 20:30 - 22:00 | Poster Session I |
| Tuesday 5 October | |
| Session 3: Actin Dynamics and Organisation II | |
| 09:00 – 09:30 | Klemens Rottner - Helmholtz Centre for Infection Research, DE Analysis of Arp2/3-complex function in protrusion |
| 09:30 - 09:45 | John Heuser - Washington University, US Revisiting the ultrastructure of the cytoskeleton (short talk) |
| 09:45 - 10:00 | Rhoda Hawkins - University of Bristol, UK Rebuilding cytoskeletal roads: Active-transport-induced polarisation of cells (short talk) |
| 10:00 – 10:15 | Keren Kinneret - Technion Israel Institute of Technology, IL Actin disassembly “clock" determines lamellipodial morphology (short talk) |
| 10:15 - 10:30 | Florian Huber - University of Leipzig, DE Actin network formation within cell-sized droplets: from star-like clusters to ladder-like stripes (short talk) |
| 10:30 - 10:45 | Group Photo |
| 10:45 - 11:15 | Coffee break |
11:15 - 11:45 | Anne Ridley - King's College London, UK Regulation of cytoskeletal dynamics by Rho GTPases |
| 11:45 - 12:15 | Pekka Lappalainen - Institute of Biotechnology Helsinki, FI Assembly and dynamics of actin stress fibers |
| 12:15 - 12:30 | Evelyne Bloch-Gallego - Institut Cochin, FR Role of netrin-1, its receptor DCC, tubulin modifications and RhoGTPases in the oriented migration of hindbrain neurons (short talk) |
| 12:30 | Lunch |
| Session 4: Forces and Cell Adhesion in Biology | |
| 15:30 - 16:00 | Coffee break |
| 16:00 - 16:30 | Pierre-François Lenne - Institut de Biologie du Développement de Marseille Luminy, FR Force generation and transmission during tissue morphogenesis |
| 16:30 - 16:45 | Antonio Schepis - Stanford University, US Alpha-E-catenin is required for gastrulation cell movement in zebrafish (short talk) |
| 16:45 - 17:00 | Di Jiang - University of Bergen, NO Regulation of actin dynamics by actin binding proteins in actomyosin contractile ring that drives notochord cell elongation (short talk) |
| 17:00 - 17:15 | Bo Dong - University of Bergen, NO N-WASP-dependent actin dynamics serves as a switch for extracellular lumen or intracellular vacuole formation during ascidian notochord tubulogenesis (short talk) |
| 17:15 - 17:30 | Sasha Bershadsky - Weizmann Institute, IL Focal Adhesions as mechanosensors (short talk) |
| 17:30 - 17:45 | Ronen Zaidel-Bar - Mechanobiology Institute, SG Regulation of cell-cell adhesion and the cytoskeleton during C. elegans morphogenesis (short talk) |
| 17:45 - 18:00 | Pere Roca-Cusachs - Columbia University, US Depletion of alpha-actinin reveals two mechanotransduction steps in cell adhesion (short talk) |
| 19:00 | Dinner |
| 20:30 - 22:00 | Poster Session II |
| Wednesday 6 October | |
| Session 5: Force Generation and Cellular Transport | |
| 09:00 - 09:30 | Mathias Rief - Ludwigs-Maximilians-Universität München, DE Single molecule mechanics of cytoskeletal proteins |
| 09:30 - 10:00 | Christoph Schmidt - Georg-August-Universität, DE Mechanical communication between cells and environment |
| 10:00 - 10:15 | Julien Husson - Insitut Curie, FR Stiffness-adaptave force generation by primary T cell on surrogate APC: role of the TCR-CD3 complex and LFA1 integrin (short talk) |
| 10:15 - 10:30 | Ross Rounsevell, University of California Berkeley, US Reconstitution of a dynamic actin-myosin II cortex on a giant vesicle scaffold (short talk) |
| 10:30 - 11:00 | Coffee break |
| 11:00 - 11:30 | Patricia Bassereau - Insitut Curie, FR Membrane nanotubes and intracellular traffic |
| 11:30 - 11:45 | Stephanie Miserey-Lenkei - Insitut Curie, FR Rab and acto-myosin dependent fission of transport vesicles at the Golgi complex (short talk) |
| 11:45 - 12:00 | Valeria Piazza - Georg-August-University Göttingen, DE Multi-isotope Imaging mass spectrometry (MIMS) mapping of protein turnover in Hair cells reveals highly stable sterocilia (short talk) |
| 12:00 - 12:15 | Eliza Morris - Harvard University, US Transport in F-actin networks (short talk) |
| 12:15 - 12:30 | David Richmond - University of California Berkeley, US Forming vesicles with cellular features: new tools for cellular reconstitution (short talk) |
| 12:30 | Lunch |
| 14:00 | Half-Day Excursion to Girona (free time) |
| 19:00 | Dinner |
| 20:00 - 21:00 | Forward Look Plenary Discussion |
| Thursday 7 October | |
| Session 6: Microtubules and Motors I | |
| 09:00 - 09:30 | Anna Akhmanova - Erasmus Medical Centre Rotterdam, NL Control of microtubule dynamics by End Binding proteins and their partners |
| 09:30 - 10:00 | Gero Steinberg - University of Exeter, UK UK Microtubule organization and motors (kinesins) in fungal model systems |
| 10:00 - 10:30 | Carolyn Moores - Birbeck College, UK Linking kinesin motor structure and function: small loops make a big difference |
| 10:30 - 11:00 | Coffee break |
| 11:00 - 11:30 | Peter Rosenthal - NIMR, UK EM Tomography of microtubules and Weibel Palade bodies |
| 11:30 - 12:00 | Stan Burgess - University of Leeds, UK EM Studies of Dynein |
| 12:00 - 12:30 | Takashi Ishikawa - Paul Scherrer Institute, CH Molecular mechanism of flagellar/ciliary bending motion revealed by electron cryo-tomography |
| 12:30 | Lunch |
| Session 7: Microtubules and Motors II | |
| 15:30 - 16:00 | Coffee break |
| 16:00 - 16:30 | Erika Hozbaur - University of Pennsylvania, US Dual functions of dynein: vesicular motor and microtubule tether |
| 16:30 - 16:45 | Itushi Minoura - Riken Institute, JP Dissecting the weak binding state of single-headed kinesin KIF1A using mutant microtubules (short talk) |
| 16:45 - 17:00 | Jeffrey Woodruff - University of California Berkeley, US Mitotic spindle disassembly occurs via distinct subprocesses driven by the Anaphase-Promoting Complex Aurora B kinase and kinesin-8 (short talk) |
| 17:00 - 17:15 | Johanna Roostalu - University of Heidelberg, DE CIN8 is a kinesin that switches directionality in response to mechanical constraints (short talk) |
| 17:15 - 17:30 | Isabelle Palacios - University of Cambridge, UK Analysis of kinesin-1 function in vivo and in vitro (short talk) |
| 17:30 - 17:45 | Leah Gheber - Ben-Gurion University of the Negev, IL Regulation of Kinesin-5 motor protein function during mitosis (short talk) |
| 17:45 - 18:00 | Ligon Lee - Rensselaer Polytechnic Institute, US Microtubule reorganization and a switch in tubulin modification from detyrosination to acetylation as epithelial cells transition from 2D to 3D polarity (short talk) |
| 17:00 - 18:15 | David Pastre - INSERM, FR Polyamine: Microtubule interactions in the test tube and in cells (short talk) |
| 18:15 - 18:30 | Yuyu Song - University of Illinois Chicago, US Stabilisation of neuronal microtubules by polyamines and transglutaminase: its roles in brain function (short talk) |
| 19:00 | Reception and Conference Dinner |
| Friday 8 October | |
| 08:00 | Breakfast and Departure |
With support from:
