ESF-EMBO Symposium
B Cells and Protection: Back to Basics
12-17 June 2011
Final Programme |
| SUNDAY 12 June |
17:00 onwards: Registration at the ESF desk
19:00: Welcome Drink
20:00: Dinner
| MONDAY 13 June |
8.45-9.00: OPENING WORDS - Rita Carsetti
ESF Presentation: Martin Röllinghoff, Erlangen-Nuremberg Universität, DE
Session 1: The host microbe relationship: a long-standing armed peace
Chair: Rita CARSETTI, Research Center, Bambino Gesù Children Hospital, Italy
09.00-09.45: François LEULIER, Institut de Biologie du Developpement de Marseille-Luminy, France
The control of host-microbes mutualism in absence of B-cells: the Fly case
09.45-10.30: Craig JENNE, University of Calgary, Canada
Host- bacteria encounter in the blood vessels
10.30-11.00: Coffee break
11.00-11.45: Hana KOZAKOVA, Laboratory of Physiology, Immunity and Ontogenesis of Gnotobionts, ASCR, Czech Republic
Amelioration of experimentally induced allergy by colonization with probiotic bacteria
11.45-12.30: Andrew MACPHERSON, University Hospital Inselspital, CH
Exploration of the mucosal IgA response against commensal bacteria with reversible colonisation
12.30: Lunch
16.00-16.30: Coffee break
Session 2:
Chair: Andrew MACPHERSON, McMaster University, Canada
16.30-17.15: Steffen JUNG, Weizmann Institute of Science, Israel
TBC
17.15-18.00: Nils LYCKE, Göteborg University, Sweden
Mucosal IgA B cell responses revisited : Plasma and memory B cell immunity following oral immunization
19.00: Dinner
20.30-22.00: Poster session
| TUESDAY 14 June |
Session 3: B cell diversity: “B” different
Chair: Deborah DUNN-WALTERS, Kings College London School of Medicine, United Kingdom
09.00-09.45: Hedda WARDEMANN, Max Planck Institute for Infection Biology, Germany
The antibody repertoire of antigen experienced B cells in health and disease
09.45-10.30: Nicolaas A. BOS, University Medical Center Groningen, The Netherlands
The site specificity of the IgA repertoire
10.30-11.00: Coffee break & Group Photo
11.00-11.45: Jo SPENCER, Kings College London School of Medicine, United Kingdom
Generation of diversity in mucosal immunoglobulin
11.45-12.15: Mikael SIGVARDSSON, Linköping University, Sweden
Shaping-up a lineage: Molecular regulation of B-lymphocyte Commitment
12.30: Lunch
15:00-16:30: Short Oral Presentations
Chair: Deborah DUNN-WALTERS
15:00-15:15: Milena Bertolotti, San Raffaele Scientific Institute, IT
Redox regulation of terminal B cell differentiation
15:15-15:30: Francesca Mion, University of Udine, IT
B lymphocytes: more than antibody producing cells
15:30-15:45: Menno van Zelm, Erasmus MC, NL
Differential impairment of antibody maturation and selection against autoreactivity in memory B cells of CD19 and CD40L deficient patients
15:45-16:00: Agata Wasik, Karolinska Institutet, SE
Different pathways-one outcome. Mantle cell lymphoma activates paraptosis alternatively to apoptosis in response to cannabinoid treatment
16:00-16:15: Adam Cunningham, University of Birmingham, UK
The role of antibody to B1b antigens against bacterial infection and its mechanism of function
16.30-17.00: Coffee break
Session 4: B cell development and function: the regulatory universe
Chair: Yehudit BERGMAN, The Hebrew University Hadassah Medical School, Israel
17.00-17.45: Deborah DUNN-WALTERS, Kings College London School of Medicine, United Kingdom
Affinity maturation changes with age
17.45-18.30: Yehudit BERGMAN, The Hebrew University Hadassah Medical School, Israel
Orchestrating immunoglobulin allelic exclusion during B cell development
19.00: Dinner
20.00-21.30: Poster Session
| WEDNESDAY 15 June |
Session 5: B cell development and function: the art of integrating signals
Chair: Almudena R RAMIRO, Spanish National Cancer Research Center, Spain
09.00-09.45: Lill MÅRTENSSON-BOPP, The Babraham Institute, United Kingdom
Signalling in Pre-B cells
09.45-10.30: Idit SHACHAR, The Weizmann Institute of Science, Israel
Molecular Mechanisms Regulating B cell Survival in Health and Disease
10.30-11.00: Coffee break
11.00-11.45: Almudena R. RAMIRO, Spanish National Cancer Research Center, Spain
MicroRNA and the regulation of AID
11.45-12.30: Francesca CHIODI, Karolinska Institutet, Sweden
Dysfunctional B cells in HIV-1 infection
12.30-13.15: Martin TURNER, The Babraham Institute, United Kingdom
Regulating B cell development and activation via RNA binding proteins
13.15: Lunch
Afternoon : Half-day excursion
19.00: Dinner
20:30-22:00: Short Oral Presentations
Chair: Maria Manuela ROSADO, Research Center, Bambino Gesù Children Hospital, Italy
20:30-20:45: Yang Zhang, University of Birmingham, UK
Setting the threshold: a role for antibody in selection of germinal centre B cells
20:45-21:00: Nancy So, University of Toronto, CA
Vigorous response of human innate-like IgM memory B cells upon infection by Neisseria gonorrhoeae
21:00-21:15: Vicky Lampropoulou, Deutsches Rheuma Forschungs Zentrum, DE
MyD88 signaling in B cells suppresses protective immunity to Salmonella infection
21:15-21:30: Alejandro Martin Gomez, Maastricht University, NL
Proteasome inhibition with Bortezomib depletes plasma cells and autoantibodies in Experimental Autoimmune Myasthenia Gravis
21:30-21:45: Tam Quach, Medizinische Hochschule Hannover, DE
Anergic responses characterize a large fraction of human autoreactive naïve B cells expressing low levels of surface IgM
| THURSDAY 16 June |
Session 6: New technologies for old problems
Chair: Mark THROSBY, Merus, The Netherlands
09.00-09.45: Rita CARSETTI/ M. Manuela Rosado
Research Center, Bambino Gesù Children Hospital, Rome, Italy
Old cells, new functions?
09.45-10.30: Mark THROSBY, Merus, The Netherlands
Development and applications of human therapeutic antibodies in infectious disease
10.30-11.00: Coffee break
11.00-11.45: Martin BACHMANN, Cytos Biotechnology AG, Switzerland
Vaccine Delivery, a question of size, geometry and molecular patterns
11.45-12.30: Maria Angeles MUNOZ-FERNANDEZ, Hospital General Universitario Gregorio Marañón, Spain
Carbosilane Dendrimers in HIV infection
13.00: Lunch
Session 7: When things go wrong: tumours and diseases
Chair: Michael CANCRO, University of Pennsylvania School of Medicine, USA
15.30-16.15: Franco LOCATELLI, Research Center, Bambino Gesù Children Hospital, Italy
TBC
16.15-17.00: Michael CANCRO, University of Pennsylvania School of Medicine, USA
Roles for the BLyS/BAFF family in antigen experienced B cell subsets
17.00-17.30: Coffee break
17.30-18.15: Michael EHRENSTEIN, University College London, United Kingdom
Secreted IgM as regulator of autoimmune responses
18.15-19.00: Hiepe FALK, University of Berlin, Germany
Long lived plasma cells and autoimmunity
19.30: Drinks Reception
20.00: Conference Dinner
| FRIDAY 17 June |
Breakfast and departure
Partnership
This conference is organised by the European Science Foundation (ESF) in partnership with the European Molecular Biology Organization (EMBO).
With Support from
