ESF-EMBO Symposium
Antiviral RNAi: From Molecular Biology Towards Applications
Programme |
| Monday 11th June | |
| 17:00 - 19:00 | Registrations at ESF desk |
| 19:00 | Welcome Drink |
| 20:00 | Dinner |
Tuesday 12th June | |
| 08.45-09.00 | Conference Opening |
Session I : RNAi and viral infections in mammals Chair: B. Berkhout, Academic Medical Center, University of Amsterdam, NL | |
| 09.00-09.30 | M. Kay, Stanford University, US RNAi approaches for HCV Infection- Is the anti-genome a viable target? |
| 09.30-10.00 | A. Russo, Second University of Naples, IT Role of cellular microRNAs in hepatitis B virus infection |
| 10.00-10.30 | Y.P. Liu, University of Amsterdam, NL Dicer-independent processing of shRNAs |
| 10.30-11.00 | Coffee Break |
| 11.00-11.30 | K.-T. Jeang, The National Institutes of Health, US Long- and short- non-coding RNAs and other factors that modulate mammalian viral replication |
| 11.30-12.00 | Y. Bennasser, Institute of Human Genetics, FR HIV uses cellular miRNAs to better replicate |
| 12.00-12.30 | S. Pfeffer, CNRS, FR Roles and regulation of microRNAs in viral infections |
| 12.30-12.50 | W. Kamel, Uppsala University, SE The adenovirus VA RNAI derived miRNAs are not required for lytic virus growth |
| 12.50-15.00 | Lunch |
Session 2 RNAi and viral infections beyond mammals Chair J.A. Garcia, Centro Nacional de Biotecnologia, Campus de la Universidad Autonoma, ES | |
| 15.00-15.30 | M.-A. Felix, CNRS-University of Paris-Diderot, FR Viral infections of Caenorhabditis nematodes |
| 15.30-16.00 | R. van Rij, Radboud University, NL Defense and counter-defense in the RNAi-based antiviral immune system of insects |
| 16.00-16.20 | J. Van Mierlo, Radboud University Nijmegen, NL Convergent evolution of Argonaute-2 Slicer antagonism in two insect RNA viruses |
| 16.20-16.50 | Coffee break |
16.50-17.10 | E. Schnettler, MRC- University of Glasgow, UK Characterization of the antiviral RNA silencing response in an Ixodes scapularis tick cell line |
| 17.10-17.30 | E. Girardi, Université de Strasbourg, FR Identification of viral small RNAs from an arthopod-borne RNA virus in mammalian cells |
| 17.30-17.50 | W. Chen, Chang Gung University, TW Additive protection by antioxidant and apoptosis-inhibiting effects on mosquito cells with dengue 2 virus infection |
| 17.50-18.20 | T. Dalmay, University of East Anglia, UK Reducing sequencing bias of small RNAs |
| 18.30-20.30 | Dinner |
| 20.30-22.00 | Poster Session |
| Wednesday 13th June | |
| Session 3 Counter defence and counter-counter defence in viral infections Chair: R. van Rij, Radboud University, NL | |
| 08.45-09.15 | Th. Hohn, University of Basel, CH Plant DNA viruses, silencing and silencing suppression |
| 09.15-09.45 | J.A. Garcia, Centro Nacional de Biotecnologia CSIC, ES Host specific functions of potyvirid HC and P1 proteins in RNA silencing suppression... and something else |
| 09.45-10.05 | E. Truve, Tallinn University of Technology, EE Human RNase L inhibitor is a suppressor of RNA silencing |
| 10.05-10.35 | Coffe break and group photo |
| 10.35-11.05 | J. Burgyan, Ministry of Rural Development, HU Small RNAs and their targets in virus infected plants |
| 11.05-11.25 | V. Pantaleo, Istituto di Virologia Vegetale del CNR, IT Genome-wide identification of host transcripts targeted by viral siRNAs in V. vinifera |
| 11.25-11.55 | S. Elena, Instituto de Biología Molecular y Celular de Plantas (CSIC-UPV), ES Population Dynamics of Virus Escape Mutants in RNAi-mediated Resistant Plants |
| 11.55-12.15 | A. Voloudakis, Agricultural University of Athens, GR COST FA0806-Plant virus control employing RNA-based vaccines: A novel non-transgenic strategy |
| 12.30-14.30 | Lunch |
| 14.30-16.30 | COST meeting |
| 16-30-17.00 | Coffee break |
| Session 4 : Interplay between RNAi and other antiviral defence mechanisms Chair: J. Kurreck, Institut für Biotechnologie, Technische Universität Berlin, DE | |
| 17.00-17.30 | J-L. Imler, Université de Strasbourg / CNRS, FR Antiviral silencing in insects |
| 17.30-17.50 | C. Donald, University of Glasgow, UK The role of mosquito innate immune response in controlling arbovirus infection and replication |
| 17.50-18.20 | P. Fortes, CIMA/UNAV, ES Increased inhibition of gene expression by combining RNAi and U1i |
| 18.20-18.50 | C. Coch, Universitätsklinikum Bonn, DE Rational design of synthetic ligands for the innate immune receptor RIG-I as novel antiviral treatment |
| 19.00-20.30 | Dinner |
| 20.30-22.00 | Poster Session |
Thursday 14th June | |
|---|---|
| 09.00-09.30 | A. Gatignol, McGill University, CA RNA interference, RNA editing and PKR pathways in viral infections |
| 09.30-10.00 | A. Karlas, Max-Planck-Institute for Infection Biology, DE Global identification of host cell factors essential for influenza A virus replication |
| 10.00-10.20 | S. Ponia, National Institute of Immunology, IN Modular Organization of Host - Pathogen interaction in HIV-1 mediated RNAi Perturbation |
| 10.20-10.50 | Coffee break |
Session 5 Towards therapeutics Chair K.-T. Jeang, The National Institutes of Health, US | |
| 10.50-11.20 | R. Adamiak, Polish Academy of Sciences, PL Fully automated 3D RNA structure prediction of the lentiviral leaders |
| 11.20-11.40 | A. Kurzynska, Institute of Bioorganic Chemistry, PL Regulation of microRNA biogenesis by RNA oligonucleotides |
| 11.40-12.10 | T. Koch, Santaris Pharma A/S, DK Locked Nucleic Acid: MicroRNA as target for treatment of hepatitis C virus infection |
| 12.30-14.30 | Lunch |
| 14.30-15.00 | D. Grimm, University of Heidelberg, DE Tailoring of Adeno-associated viruses as anti-viral RNAi reagents |
| 15.00-15.30 | J. Kurreck, Technische Universität Berlin, DE Combinatorial RNAi approaches against coxsackievirus B3 |
| 15.30-16.00 | B. Berkhout, University of Amsterdam, NL RNAi based gene therapy for HIV-AIDS |
| 16.00-16.30 | J. De Vicenzo, University of Tennessee, US RNA interference strategies for human respiratory syncytial virus: Establishing proof of principle in man and progress of ongoing clinical trials |
| 16.30-17.00 | Coffee break |
| 17.00-18.30 | Poster Session and Poster Prizes |
| 18.30-19.30 | Future perspectives and general discussion |
| 20.00 | Conference dinner |
| Friday 15 June | |
| 08:00 | Breakfast and Departure |
