ESF Research Conferences

ESF-EMBO Symposium with the support of EFIS

B Cells From Bedside To Bench And Back Again

2-7 September 2013

Polonia Castle in Pultusk, Poland

Preliminary Programme

Monday 2 September
17:00–19:00Registration at the ESF Desk                          
19.00Welcome Drink
20:00Dinner
Tuesday 3 September
08:45-08:55

The ESF Conference Scheme
Martin Roellinghoff, Erlangen-Nuremberg Universität, DE

08:55-09:00

Opening Remarks
Deborah Dunn-Walters, King's College London, UK

Session I - Revelations from the bedside
Chair: Claudia Mauri
, University College London, UK
09:00-09:45

Ludvig Sollid, University of Oslo, NO
Environmental control of the celiac disease antibody response

09:45-10:30

Qiang Pan-Hammarstroem, Karolinska Institutet, SE
DNA repair genes are selectively mutated in human B cell lymphomas

10:30-11:00Coffee Break
11:00-11:45

Andrew Chan, Genentech, US
B cell immunotherapy- insights from the clinic

11:45-12:30

Sai Reddy, ETH Zurich, CH
Systems Immunology Approach for Antibody Discovery and B cell Repertoire Analysis

12:30Lunch
Keynote Session
14:30-15:15Frances Lund, University of Rochester, US
Cytokine Producing Effector B Cells in Health and Disease

Session II - Regulation and Communication
Chair:
Jo Spencer, King's College London, UK

15:15-16:00

Ramit Mehr, Bar-Ilan University, IL
Insights from bioinformatical analyses of immunoglobulin genes in autoimmune and inflammatory diseases

16:00-16:30Coffee break
16:30-17:15

Yves Renaudineau, Brest University, FR
Dual role of STIM1 in B cells from systemic lupus erythematosus patients

17:15-18:00    

Claudia Mauri, University College London, UK
The role of microbiota in the differentiation of regulatory B cells

19:00Dinner
20:30-21:30

Poster Session 1 - Odd Numbers

Wednesday 4 September

Session II continued - Regulation and Communication
Chair: Ludvig Sollid, University of Oslo, NO

09:00-09:45 

Richard Lo-Man, Institut Pasteur, FR
From mice to men, regulatory B cells control early life immunity

09:45-10:30

Frank Emmert-Streib, Queen's University Belfast, IE
Inferring and analyzing the gene regulatory network in B-cell lymphoma

10:30-11:00Coffee break
11:00-11:45

Padraic Fallon, Trinity College Dublin, IE
B cells and T Follicular Helper Cells

11:45-12:30

Christophe Jamin, Brest University, FR
Regulation of Follicular Helper T Cells by human B Lymphocytes

12:30Lunch
Session III  -  Short talks from early career stage researchers
Chair: Ramit Mehr, Bar-Ilan University, IL
14:30-14:50Achilleas Floudas, University of Newcastle, Uk
Altered B cell populations and cytokine production in primary biliary cirrhosis patients
14:50-15:10

Wagdi Almishri, University of Calgary, CA
Novel regulatory role of B cells in the context of hepatic innate immune cell activation and inflammation

15:10-15:30Britt de Jong, Academic Centre for Dentistry Amsterdam, NL
Dissecting abnormal immunoglobulin responses in destructive periodontal disease
15:30-15:50Agata Wasik, Karolienska Institute, SE
Deciphering the role of the endocannabinoid system in mantle cell lymphoma
15:50-16:30Coffee break and Group Picture
16:30-16:50Saravanan Yuvaraj, Erasmus Medical Centrum, NL
Evidence for B-1 B cell contribution to chronic lymphocytic leukemia by usage of VH11-2/VK14-129 stereotypic BCR
16:50-17:10Srividya Swaminathan, University of California, US
BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint
17:10-17:30

Louise Humpert, University of Bern, CH
Functional role of CXCR7 expression on late germinal center B cells

17:30-17:50

Konstantia-Maria Chavele, University College London, UK
Circulating plasmablasts induce the differentiation of human CD4+ T follicular helper cells via secretion of IL-6

19:00Dinner
Keynote Session
20:30-21:30

Lucia Mincheva-Nilsson, Umeå University, SE
Exosomes - friend or foe?

21:30Informal careers discussion for young researchers       
Ramit Mehr, Bar-Ilan University, IL
Thursday 5 September
Session IV - New insights into antibody function   
Chair:
Richard Lo-Man, Institut Pasteur, FR
09:00-09:45

Rita Carsetti, University of Tor Vergata, IT
The importance of being IgM

09:45-10:30

Jo Spencer, King's College London, UK
B cells in human gut associated lymphoid tissue

10:30-11:00 Coffee Break
11:00-11:45

Andreas Cerutti, Barcelona Biomedical Research Park, ES
New insights in the regulation and function of IgD

11:45-12:30Edwin Hawkins, Imperial College London, UK
Epigenetic manipulation of pathogenic and protective antibody responses
12:30Lunch
13:30Half-day Excursion to Warsaw and the Royal Castle
19:30   Dinner
20:30-22:00Poster session 2 - Even Numbers
Friday 6 September
Session V - B cell microenvironment- regulation of differentiation, survival and function
Chair:
Rita Carsetti, University of Tor Vergata, IT
09:00-09:45

Stephane Mancini, Faculté des Sciences de Luminy, FR
Stromal cells for survival at developmental checkpoints

09:45-10:30

Deborah Dunn-Walters, King's College London, UK
Changes in B cell repertoire with age

10:30-11:00 Coffee Break
11:00-11:45

Idit Shachar, The Weizmann Institute of Science, IL
Molecular Mechanisms Regulating B cell Survival in Health and Disease

11:45-12:30

Bernd Schroeder, Christian-Albrechts-University of Kiel, DE
The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain CD74

12:30Lunch
Session V continued - B cell microenvironment- regulation of differentiation, survival and function
Chair:
Idit Shachar, The Weizmann Institute of Science, IL
14:30-15:15

Claudia Berek, DRFZ, DE
Accessory cells for plasma cell survival

15:15-16:00

Ken Duffy, Hamilton Institute, IE
Competition, Censorship and B Cell Fates

16:00-16:30Coffee break
16:30-17:15

Mikael Karlsson, Karolinska Institutet, SE
Suppression of B cells by iNKT

17:15-18:00

Forward Look and Conference Closure
Idit Shachar, The Weizmann Institute of Science, IL

20:00Conference Dinner
Saturday 7 September

Breakfast and Departure