FEBS Workshop

Biological Surfaces and Interfaces

30 June - 05 July 2013

Hotel Eden Roc, Sant Feliu de Guixols, Catalonia, Spain

Chair: Ralf Richter CIC biomaGUNE, ES, J. Fourier University, FR and MPI for Intelligent Systems, DE

Co-Chair: Catherine Picart, Grenoble INP, FR

Vice-Chairs: Eva-Kathrin Sinner, BOKU, AT; Katharina Maniura, EMPA, CH

Final Programme

Sunday 30 June
17:00-19:30 Registration at the ESF Desk  
19:00Welcome Drink
20:00Dinner
Monday 1 July
08:35-08:50

Welcome & Information

08:50-09:55

KEYNOTE LECTURE I - Chair: Ralf Richter,
CIC biomaGUNE, ES
Alain BRISSON
, UMR-CBMN CNRS-Université Bordeaux 1, FR
A 25-year long journey with Annexin-A5: from structure to membrane repair and applications in disease detection

Session 1: Engineering biointerfaces
Chair: Catherine Picart,Grenoble INP, FR

09:55 –10:30Janos VÖRÖS, ETH Zürich, CH
Controlling the biointerface using potentials and currents
10:30-11:00Coffee break
11:00 –11:55

Jason BURDICK, University of Pennsylvania, US
Hydrogel Interfaces to Control Stem Cell Interactions

11:55 –12:30

Karine GLINEL, Université Catholique de Louvain, BE
Surfaces Engineered at the Nano/Micrometer Scale to Control Bacterial and Mammalian Cell Behaviors

12:30Lunch & Free Time
15:45 –16:15Coffee break

Session 2 – Glycoscience and biointerfaces
Chair: Ralf Richter,CIC biomaGUNE, ES

16:15 –17:10

Anthony DAY, University of Manchester, UK
Structural and functional insights into sugar-protein networks in inflammation and ovulation

17:10 –17:45

Katharina RIBBECK, Massachusetts Institute of Technology, US
Mucin polymers for bioinspired filters and coatings

17:45-18:35Heike WALLES, University of Würzburg, DE
Influence of ECM components on engineering of 3D tissue and cancer models
18:55 –20:25Dinner
20:25 –21:20Bruno ANTONNY, CNRS & Université de Nice Sophia Antipolis, FR
Self-organization of biochemical reactions by membrane curvature
21:20 Poster Session I & Drinks reception
Tuesday 2 July

Session 3: Fundamentals of interfacial behavior and interactions
Chair: Ilya Reviakine, CIC biomaGUNE, ES

09:00-09:55

Christine ORTIZ, Massachusetts Institute of Technology, US
Morphometrically-controlled biological and bio-inspired suture joint interface in armor

09:55-10:30

Mirjam LEUNISSEN, FOM Institute AMOLF, NL
The entropic impact of tethering, multivalency and dynamic recruitment in systems with specific binding groups

10:30-11:00Coffee break
11:00-11:55

Mark BIGGS, Adelaide University, AU

Molecular modeling of protein adsorption: from fundamentals to desing

Session 4: Contributed Talk Session I
Chair: Eva Sinner, BOKU, AT

11:55-12:10   Thomas CROUZIER, Massachusetts Institute of Technology, US
A PEG-based molecular patch for the mucosa
12:10-12:25

Biomat Grant
Jasmine SEROR
, Weizmann Institute of Science, IL
Molecular origins of biolubrication

12:30Lunch & Free Time
15:30-16:00Coffee break

Session 4: Contributed Talk Session I (continued)

16:00-16:15Sponsor Talk TECAN – Presented by Denis Coulet
Target-based drug activity and post-translational and transcriptional analysis using ex vivo Alvetex®Scaffold three-dimensional cell culture technology
16:15-16:30

Sponsor TalkJPK INSTRUMENTS – Presented by Carmen Pettersson
QI™- New generation of quantitative nanomechanical atomic force microscopy measurements in high resolution

16:30-16:45

Sponsor Talk – CYTOSURGE - Presented by Michael Gabi
FluidFM Technology

16:45-17:00Manuel SALMERON-SANCHEZ, University of Glasgow, UK
Functional living biointerfaces
17:00-18:40Poster Session I (continued)
18:55-20:25  Dinner
20:25-21:30

KEYNOTE LECTURE II - Chair: Catherine Picart,Grenoble INP, FR
Dennis DISCHER
, University of Pensylvania, US
'Self' versus 'Foreign' and Soft versus Stiff Interfaces - from survival to differentiation

21:30Poster Session I (continued)/Poster Session II
Wednesday 3 July

Session 5: Biointerfaces – cells, cell targeting and medical applications
Chair: Jason Burdick, University of Pennsylvania, US

09:00-09:55THE EMBO LECTURE
Fiona WATT
, Kings College London School of Medicine, UK
Intrinsic and extrinsic control of epidermal stem cell fate
09:55-10:30

Ilya REVIAKINE, CIC biomaGUNE, ES
Form lipids to platelets: interactions between biological model systems and inorganic oxides

10:30-11:00Coffee break
11:00-11:55Andrès GARCIA, Georgia Institute of Technology, US
Biofunctional materials for cell delivery and tissue repair
11:55-12:30Jesus PEREZ GIL, Universidad Complutense de Madrid, ES
Understanding the molecular mechanisms at the breathing air-liquid interface to develop novel therapeutic tools in respiratory medicine
12:30-12:40

Patrick van Dijk, University of Leuven, BE
Presentation of FEBS

12:40 Lunch
14:00Excursion to the Dalí Theatre-Museum in Figueres
18:55-20:25Dinner
20:30-20:40

ESF Presentation
Rapporteur: Jakob Schweizer, University of Oxford, UK

20:40-21:30

Forward Look Plenary Discussion - Chair: Katharina Maniura, Swiss Federal Institute for Materials Science and Technology, CH and Eva Sinner, BOKU, AT

With discussion input from: Jacob Israelachvili, Dennis Discher and others

21:30Poster Session II (continued)
Thursday 4 July

Session 6: Nanoscale characterization of interfaces and bioentities
Chair: Janos Vörös, Institut f. Biomedizinische Technik - ETZ F 82, CH

09:00-09:55

Yves DUFRÊNE, Université Catholique de Louvain, BE
Atomic force microscopy: a nanoscopic window on the cell surface

09:55-10:30

Sylvie ROKE, EPFL STI IBI-STI LBP, CH
Nonlinear spectroscopy and imaging of soft and living systems

10.30Coffee break
11:00-11.55Fredrik HÖÖK, Chalmers University of Technology, SE
Label-free biomolecular interaction analysis and equilibrium-fluctuation-based single-molecule studies of cell-membrane mimics

Session 7: Contributed Talk Session II
Chair: Katharina Maniura, Swiss Federal Institute for Materials Science and Technology, CH

11:55-12:10Mirren CHARNLEY, Swinburne University of Technology, AU
Exploring cell behaviour using microfabricated cell culture platforms
12:10-12:25Erdem KARABULUT, KTH Royal Institute of Technology, SE
Adhesive layer-by-layer films of carboxymethylated cellulose nanofibril-dopamine covalent bioconjugates inspired by marine mussel threads
12.30Lunch & Free Time
15:30-16:00Coffee break

Session 7: Contributed Talk Session II (continued)

16:00-16:15Galina DUBACHEVA, CIC biomaGUNE, ES
Host-guest model systems to understand multivalent interactions at the cell-hyaluronan matrix interface
16:15-16:30Björn AGNARSSON, Chalmers University of Technology, SE
Evanescent-wave excitation for single molecule observations and kinetics on functionalized surfaces
16:30-16:45Giorgia BRANCOLINI, CNR - Institute Nanoscience, IT
Molecular simulations of the pathological self-aggregation of β2-microglobulin
16:45-17:00Thomas BOUDOU, CNRS - Grenoble Institute of Technology, FR
Generation and optimization of engineered 3D skeletal muscle microtissues
17:00-18:55Poster Session II (continued)
18:55-20:00

KEYNOTE LECTURE III - Chair TBA
Jacob ISRAELACHVILI
, University of California Santa Barbara, US
Breakthroughs and belly flops in understanding biomolecules and biosurface interactions

20.00Drinks Reception & Workshop Dinner
Friday 5 July
Breakfast & Departure

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