Integrated Approaches for Functional Genomics

Grants Awarded

The following grants have been awarded within the framework of the Programme:

2005 

Ref.

Grantee

Host

Project Title

2005/579

Daniel CORCOS, Hôpital Cochin, Paris (FR)

Marianne BRUGGEMANN, Babraham Institute, Cambridge (UK)

Purification of B-cell receptor ligands

2005/485

Harold CREMER, Developmental Biology Institute, CNRS, Marseille (FR)

Andreas BOSIO, Memorec Biotec Company, Cologne (DE)

Functional Genomics approach to generate new markers for neuronal subpopulations

2005/618

Marco FERG, Institut für Toxikologie und Genetik , Forschungszentrum Karlsruhe (DE)

Elia STUPKA, Telethon Institute of Genetics and Medicine (TIGEM), Napoli (IT)

The elucidation of the mechanisms of promoter recognition in differential gene expression during vertebrate embryo development

2005/602

Petr HALADA, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague (CZ)

Ole NØRREGAARD JENSEN, Department of Biochemistry & Molecular Biology, University of Southern Denmark, Odense (DK)

 Mass spectrometry-based approach to phosphoproteome analysis of cancer cells after cyclin-dependant kinase inhibition

2005/612

Linda OTTOBONI, Department of General Pathology, University of Verona (IT)

Jörg HOHEISEL, Deutsches Krebsforschungszentrum, Heidelberg (DE)

Analysis of signal transduction networks involved in the adhesion of encephalitogenic lymphocytes by using system biology approaches

2005/603

Stephan PHILIPPI, Computer Science Faculty, University of Koblenz (DE)

Chris RAWLINGS, Rothamsted Research, Harpenden (UK)

Modelling and Simulation of Biological Networks

2005/486

Andre SKUSA, NRW International Graduate School in Bioinformatics and Genome Research, University of Bielefeld (DE)

Jacob KOEHLER, Rothamsted Research, Herpenden (UK)

Extracting cell-cell interaction networks from texts using ONDEX

2005/481

Mikhail SOLOVIEV, School of Biological Sciences, University of London (UK)

Piero MORANDINI, Department of Biology "L. Gorini", University of Milan (IT)

 Novel data handling approach reveals co-regulation of gene expression in metabolic pathways: application for engineering of plant metabolism

2005/592

Andrea SPLENDIANI, University of Milano-Bicocca (IT)

Benno SCHWIKOWSKI, Institut Pasteur, Paris (FR)

Network-based functional analysis of gene expression data

2005/606

Gaetano TRIPOLI, Telethon Institute of Genetics and Medicine, Napoli (IT)

Ferenc MULLER, Institute of Toxicology and Genetics, Karlsruhe (DE)

Characterization of novel gene regulation paradigms in zebrafish embryos

2005/615

Juan M. VAQUERIZAS, Bioinformatics Unit, CNIO, Madrid (ES)

Nicholas M. LUSCOMBE, EMBL-European Bioinformatics Institute, Hinxton (UK)

A computational study of transcription regulation in vertebrate genomes: Integrating genomic sequence, microarray and SNP data

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2004 

Ref.

Grantee

Host

Project Title

2004/420

Andrea CHINI, ICMB, University of Edinburgh (UK)

Roberto SOLANO, Centro Nacional de Biotecnologia, CSIC, Madrid (ES)

Gene Profiling Analysis of Activated Disease Susceptibility Arabidopsis mutant in response to Pythium infection

2004/198

Francisco Manuel CODONER, Instituto de Biología Molecular y Celular de Plantas, Valencia (ES)

Mario FARES, Molecular Evolution and Bioinformatics Laboratory, NUI Maynooth (IE)

Predicting protein-protein contact

2004/303

Anna GERASIMOVA, Laboratory of Bioinformatics, State Scientific Center GosNIIGenetika, Moscow (RU)

Gavin H. THOMAS, Department of Biology, University of York (UK)

An integrated study of the regulation of respiration in Haemophilus influenzae

2004/421

Malgorzata JAREMKO, Institute of Molecular Technologies, University of Wroclaw (PL)

John FOEKENS, Josephine Nefkens Institute, Erasmus Medical Center, Rotterdam (NL)

Identification of functional pathways associated with clinical chemotherapy-resistance in breast cancer by advanced mass spectrometry

2004/322

Sara Margareta JOHANSSON, Karolinska Institute, Stockholm (SE)

Riitta LAHESMAA, Centre for Biotechnology, University of Turku (FI)

Functional and proteomic analyses of exosomes – immune regulators with a role in allergy?

2004/321

Jan KOSINSKI, Centre for Interfaculty Individual Studies in Mathematical and Natural Sciences, University of Warsaw (PL)

Peter FRIEDHOFF, Institut für Biochemie, Universität Giessen (DE)

A biophysico-chemical and bioinformatics approach to study the structure and the molecular dynamics of the muthls protein complex

2004/255

Jernej MURN, Institute of Pharmacy, University of Ljubljana (SL)

Xavier GIDROL, Laboratory of Functional Genomics, CEA, Evry (FR)

The identification of DNase responsible for internucleosomal DNA cleavage in apoptotic cells

2004/267

Cristina NIETO, Centro de Edafología y Biología Aplicade del Segura, Espinardo (ES)

Abdel BENDAHMANE, Unité de Recherche en Génomique Végétale, Evry (FR)

A genomic approach to test the interaction between host translation factors and virus avirulence determinants

2004/259

Reetta Liisa NYLUND, STUK, Helsinki (FI)

Juan Pablo ALBAR, Centro Nacional de Biotecnología, Madrid (ES)

Enhancement of use of proteomics methods in radiobiology

2004/429

Anne Marie POUPON, Institut de Biochimie et de Biophysique Moléculaire et Cellulaire, CNRS, Orsay (FR)

Alwyn T. JONES, Department of Cell and Molecular Biology, Uppsala University (SE)

Laboratory Information Management System for Structural and Functionnal Genomics

2004/406

Dimitry RODIONOV, Laboratory for Bioinformatics, State Scientific Center for Biotechnology, Moscow (RU)

Thomas EITINGER, Institut für Biologie/Mikrobiologie, Humboldt-Universität zu Berlin (DE)

Functional genomics of nickel/cobalt transport systems in bacteria

2004/332

Jasmin SARIC, EMBL, Heidelberg (DE)

Aldo GANGEMI, Institute for Cognitive Sciences and Technology, Rome (IT)

Design and formal characterisation of a core bio-ontology

2004/330

Cedric SIMILLION, Department of Plant Systems Biology, Ghent University (BE)

T. Martin EMBLEY, School of Biology, University of Newcastle (UK)

Functional characterisation of mitosome related proteins in microsporidia

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2003 

Ref.

Grantee

Host

Project Title

2003/EG/01

Daniel AGUILAR, Institut de Bioquímica i Biomedicina, Universitat Autònoma de Barcelona (ES)

Michael E. STERNBERG, Department of Biology & Biochemistry, Imperial College, London (UK)

Computational analysis of metabolic pathways

2002/EG/02

Nicola ARMSTRONG, Computation Molecular Biology Group, EUROADOM, Eindhoven (NL)

Rainer SPANG, Department of Computational Molecular Biology, Max-Planck Institute for Molecular Genetics, Berlin (DE)

Statistical methods for the identification of binding sites

2003/EG/19

Rosanna ASSELTA, Department of Biology and Genetics for Medical Sciences, University of Milan (IT)

Leena PELTONEN-PALOTIE, Department of Molecular Medicine, National Public Health Institute, Helsinki (FI)

Identifying gene variants predisposing to multiple sclerosis

2003/EG/20

Karine BASTARD, Laboratoire de Biochimie Théorique, IBPC, Paris (FR)

Martin ZACHARIAS, School of Engineering and Science, International University Bremen (DE) 

Comparison and possible integration of two complementary docking programs accounting for protein surface remodelling during association

2002/EG/03

Carole BRANCHE, Karolinska Institutet, Stockholm (SE)

Philippe BASTIN, Muséum d’Histoire Naturelle, Paris (FR)

Gene knockdowns in Trypanosomes using RNA interference

2003/EG/22

Marina CIULLO, Institute of Genetics and Biophysics "A. Buzzati-Traverso", CNR, Naples (IT)

Françoise CLERGET-DARPOUX, INSERM Unité de Recherche U535, Hôpital Paul Brousse, Villejuif (FR) 

Analysis of pedigree data and phenotype data of isolated populations

2003/EG/04

Stefanie DE BODT, Department of Plant Systems Biology, University of Ghent (BE)

Günter THEISSEN, Friedrich-Schiller Universität, Jena, Germany

Functional divergence of developmental control genes: integrating bioinformatics and functional genomics

2003/EG/05

Timothy DOWSE, Department of Biological Sciences, Imperial College, London (UK)

Andrew P. WATERS & C.J. JANSE, Leiden University Medical Centre (NL)

Establishment of a tetracycline-inducible system in Plasmodium berghei to study an essential gene involved in host cell invasion

2003/EG/06

Franca FRATERNALI, MRC, London (UK)

Daan FRENKEL, Institute for Atomic & Molecular Physics, Amsterdam (NL)

Stochastic simulations of small G-proteins cross-talk

2003/EG/27 

Anna GONZÁLEZ NEIRA, Unidad de Biologia Evolutiva, University Pompeu Fabra, Barcelona (ES)

Ian DUNHAM, The Sanger Centre, Cambridge (UK) 

Analysis of diversity of linkage disequilibrium in chromosome 22

2003/EG/30 

Michele IACONO, Dipartimento di Scienze Biomolecolari e Biotechnologie, University of Milan (IT)

Alvis BRAMA, European Bioinformatics Institute, Cambridge (UK) 

Identification of muscle-specific sequence motifs involved in transcriptional and post-transcriptional regulation of gene expression through integrated "in silico" approaches

2003/EG/33 

Anette LINDBERG, Department of Medical Biochemistry & Microbiology, Uppsala University (SE)

Hans PRYDZ, Bioteknologisenteret, University of Oslo (NO)

Short interfering RNA in model systems of relevance for cancer

2003/EG/34 

Fouzia MARZOULF-MOUSSOUNI, Laboratoire INSERM U522, Pontchaillou Hospital, Rennes (FR)

Ulf LESER, Lehrstuhl für Wissensmanagement in der Bioinformatik, Humboldt Universität zu Berlin (DE) 

Data-mining techniques for functional genomics in the liver

2003/EG/11

Jacqueline McCLUSKEY, Division of Infection & Immunity, University of Glasgow (UK)

Jean-Pierre CLAVERYS, Université Paul Sabatier, Toulouse (FR)

Microarray analysis of the pneumococcal transcriptome under different environmental stresses

2003/EG/35 

Jens Raabjerg OLESEN, Department of Molecular Biology, University of Aarhus (D

Domenico LIBRI, CGM, CNRS, Gif-sur-Yvette (FR)

Coupling between transcription and mRNA quality control in Saccharomyces cerevisiae

2003/EG/36 

Josep PAREJA GÓMEZ, Structural Bioinformatics Lab (GRIB), IMIM/UPF, Barcelona (ES)

Patrick ALOY, EMBL, Heidelberg (DE) 

 

2003/EG/12

F. Xavier PICO, Department of Ecology, University of Nijmegen (NL)

Carlos ALONSO BLANCO, Departamento de Genética Molecular de Plantas, Universidad Autónoma de Madrid (ES)

Transcriptomic analysis of flowering introgression lines in Arabidopsis

2003/EG/15

Dmitry RODIONOV, State Scientific Center for Biotechnology, Moscow (RU)

Nicole COTTE-PATTAT, Institute National des Sciences Appliquées, Villeurbanne (FR)

Regulation of pectin catabolism in the phytopathogenic bacteria Erwinia chrysanthemi

2003/EG/39 

Serkan URANBEY, Biotechnology and Plant Breeding Unit, Central Research Institute for Field Crops, Yenimahalle/Ankara (TR)

John DRAPER, Institute of Biological Sciences, University of Wales Aberystwyth (UK)  

Brachypodium distachyon as a ’test bed’ for functional analysis of wheat genes - integrating expression studies with phenotyping

2003/EG/40 

Marcin WOJCIECHOWSKI, Department of Pharmaceutical Technology and Biochemistry, Gdansk University of Technology (PL)

Alberto POLICRITI, Dipartimento di Maternatica e Informatica, Universita’ degli Studi di Udine (IT) 

Singular value decomposition as a tool for functional genomics

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2002

Ref.

Grantee

Host

Project Title

2002/EG/11

Daniel AMBORT, Institute of Biochemistry & Molcular Biology, University of Berne (CH)

Robert BEYNON, Department of Veterinary Science, University of Liverpool (UK)

Meprin - a metalloprotease and its substrates and cognate binding partners in human intestine

2002/EG/12

Francisco AZUAJE, Faculty of Informatics, University of Ulster, Jordanstown (UK)

Javier HERRERO, Bioinformatics Unit, Centro Nacional de Investigaciones Oncologicas (CNIO), Madrid (ES)

Data mining approaches to class discovery in gene expression data

2002/EG/13

Katherine BAINBRIDGE, Biology Department, University of York (UK)

Thomas MORITZ, Department of Forest Genetics and Plant Physiology, Swedish University of Agriculture, Umeå (SE)

Identification of the MAX gene-dependent long-range shoot branching inhibitor from Arabidopsis

2002/EG/14

Gerhard BRÜCKER, Insitut für Biologie, Freie Universität Berlin (DE)

Andrew CUMING, Centre for Plant Sciences, Faculty of Biological Sciences, Leeds University (UK) 

Transcriptome analysis of mutants of Physcomitrella patens

2002/EG/17

Maxime CAILLAU, Department of Animal and Plant Sciences, University of Sheffield (UK)

Bengt SÖDERSTRÖM, Department of Ecology, Lund University (SE)

The functional genomics of nutrient acquisition by the ectomycorrhizal fungus Paxillus involutus

2002/EG/02

Svetlana CHABELSKAIA , Department of Genetics, St. Petersburg State University (RU)

Michel PHILIPPE, Faculté de Médecine, Université de Rennes I (FR)

Influence of eRF3 on gene expression of Saccharomuces cerevisiae

2002/EG/20

Andreas DORN, Institute for Molecular and Clinical Virology, University of Erlangen-Nürnberg (DE)

Ulf PETTERSSON, Rudbeck Laboratory, Department of Genetics and Pathology, Uppsala University (SE)

Differential gene expression of human cells infected with adenovirus type 12

2002/EG/12

Javier HERRERO, Bioinformatics Unit, Centro Nacional de Investigaciones Oncologicas (CNIO), Madrid (ES)

Francisco AZUAJE, Faculty of Informatics, University of Ulster, Jordanstown (UK)

Data mining approaches to class discovery in gene expression data

2002/EG/07

Filiz ÖZBAS GERCECKER, DNA/Cell Bank & Gene Research Laboratory, Faculty of Medicine, Hacettepe University, Ankara (TU)

Eleonora ARONICA, Academic Medical Centre, Institute Pathology, University of Amsterdam (NL)

Serial analysis of gene expression (SAGE) in the hippocampus of patients with mesial temporal sclerosis

2002/EG/24 

Simona PANNI, Dipartimento di Biologia, Università degli Studi di Tor Vergata, Roma (IT)

Jean SCHNEIDER-MERGENER, Institut für Medizinische Immunologie Charite, Humboldt-Universität Berlin (DE) 

A combined genomic strategyu to elucidate the binding specificity of yeast domains involved in signal transduction

2002/EG/09 

Mikhail Aleksandrovich POLZIKOV, Laboratory of Structural Biochemistry, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow (RU)

C. Babis MAGOULAS, Neuroscience Centre, Department of Neurosurgery, Queen Mary University of London (UK)

Functional analysis of Surf-6 by transgenic targeted disruption in mouse embryonic stem (ES) cells

2002/EG/27 

Christine Beate RAUSCH, Institute of Plant Sciences, Federal Institue of Technology (ETH), Lindau (CH)

Lothar WILLMITZER & Mark STITT, Max Planck Institute for Molecular Plant Physiology, Golm (DE)

Transcriptional and metabolig profiling of an Arabidopsis pht2;1 knock-out mutant

2002/EG/28 

George TSIAMIS, Department of Environmental and Natural Resources, University of Ioannina, Agrinio (GR)

John W. MANSFIELD, Department of Agricultural Sciences, Imperial College at Wye

Identification and analysis of plant proteins involved in pathogen recognition

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2001 

Ref.

Grantee               

Host

Project Title

2001/EG/02

Andrea CABIBBO, Dipartimento di Biologia, Universita’ di Roma "Tor Vergata", Rome (IT)

Jens SCHNEIDER-MERGENER, Institut für Medizinische Immunologie Charite, Humboldt-Universität Berlin (DE)

Characterisation of the specificity of phosphoserines
/threonines binding modules by screening of immobilised peptide repertoires

2001/EG/03

Kari ESPOLIN FLADMARK, Department of Anatomy and Cell Biology, University of Bergen (NO)

Joël VANDEKERCKHOVE, Flanders Interuniversity / Institute for Biotechnology, Ghent University (BE)

Identification of phosphorylated cytoskeleton components in apoptotoc hepatocytes after exposure to phosphatase inhiniting cyanobacterial toxins

2001/EG/05

Lenka HERNYCHOVA, Institute for Radiobiology and Immunology, Purkyne Military Medical Academy, Techonin (CZ)

Karin HJALMARSSON, Department of NBC-Analysis, The Swedish Defence Research Agency (FOI), Umea (SE)

Construction of a Francisella tularensis two-dimensional electrophoresis protein database

2001/EG/06

Petr JANSA, Department of Mammalian Molecular Genetics, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague (CZ)

Heinz HIMMELBAUER & Wilfried NIETFELD, Abteilung Lehrach, Max-Planck-Institut für Molekulare Genetik, Berlin-Dahlem (DE)

Cross-species concept in the mouse functional genomics: Construction of a genomic cosmid library from Mus m. musculus and expression profiling in inter-species hybrids

2001/EG/08

Lucilla NOBBIO, Department of Neurological and Vision Sciences, University of Genova (IT)

Vincent TIMMERMAN, Peripheral Neuropathy Group, Molecular Genetics Laboratory, University of Antwerpen (BE) & Paul VAN HUMMELEN, VIB MicroArray Facility, Leuven (BE) 

Gene expression analysis of in vivo and in vitro models of Charcot-Marie-Tooth 1A (CMT 1 A) disease, using cDNA microarrays

2001/EG/13

Monica SLOMINSKA, Department of Molecular Biology, University of Gdansk (PL)

Kirsten SKARSTAD, Department of Cell Biology, Institute for Cancern Research, Radium Hospital, Oslo (NO) 

Escherichia coli SeaA protein as a global regulator of transcription

2001/EG/16

David DREW, Arrhenius Laboratoires, Department of Biochemistry and Biophysics, Stockholm (SE)

Edmund R.S. KUNJI, Dunn Human Nutrition Unit, Medical Research Council, Cambridge (UK)

High-throughput membrane protein overexpression in Lactococcus lactis

2001/EG/17

Lyudmila NAYCHOVA GEORGIEVA, Department of Medical Genetics, University Hospital "Maichin Dom", Sofia (BG)

Georg KIROV, Neuropsychiatric Genetics Unit, Department of Psychological Medicine, College of Medicine, University of Wales, Cardiff (UK)

Identifying promoter polymorphisms that increase susceptibility to manic depressive illness: linking a functional genomics approach with high-throughput genotyping methods

2001/EG/22

Robert MOLIDOR, Institute of Biomedical Engineering, Graz (AT)

Jérôme GALON, Centre de Recherches Biomédicales des Cordeliers, Paris (FR)

Identifying gene expression patterns in anergic T-cells and tumoral micro-environment T-cells: establishing infrastructure for computational analysis

2001/EG/23 

Juan Ramón PEINADO MENA, Department of Cell Biology, University of Córdoba (ES)

Hubert VAUDRY, Laboratory of Cellular and Molecular Neuroendocrinology, European Institute for Peptide Research, University of Rouen, Mont-Saint-Aignan (FR)

Frog melanotroph cell as a model to elucidate the molecular basis of secretory plasticity of endocrine cells

2001/EG/25 

Sanjay Adrian SALDANHA, Chemistry Department, Cambridge University (UK)

Robert B. RUSSEL, EMBL, Heidelberg (DE) 

Probing and predicting enzyme specificity in genomes

2001/EG/26 

Oleg. V. TIMOFEEV, Department of Genetics, Faculty of Biology and Soil Science, St. Petersburg State University (RU)

Dieter BROCKMANN,  Institute of Molecular Biology, University of Essen Medical School (DE)

Screening cDNA libraries derived from E1A+cHa-ras or E1A+E1B19kD transformed cells differing in cell-cycle checkpoint control for identification of cell-cycle regulating proteins interacting with adenoviral proteins E1A and E1B19kD

2001/EG/27 

Eva VONDRUSKOVA, Institute of Parasitology, Czech Academy of Sciences, Ceske Budejovice (CZ)

Rob BENNE, Academic Medical Center, Department of Biochemistry, University of Amsterdam (NL)

Functional analysis of guide RNA-binding proteins in Trypanosoma brucei using RNA interference

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