Drug molecules seldom act simply on one protein but on protein complexes and networks. A deeper understanding of these ‘cooperative assemblies’ should lead to better targeting of drugs [more]
A map of where proteins are located in tissues and cells could help scientists understand the molecular basis of diseases such as cancer [more]
For centuries man has had a uniquely close relationship with dogs – as a working animal, for security and, perhaps most importantly, for companionship. Now, dogs are taking on a new role – they are helping in the hunt for genetic mutations that lead to diseases in humans.“Dogs get very similar... [more]
Impressive advances in our understanding of the genetic basis of disease were outlined at the 3rd ESF Functional Genomics Conference in Innsbruck, Austria [more]
Ubiquitous fungus Aspergillus fumigatus poses an increasing threat to patients with compromised immune systems [more]
Recent advances in genetic screening will lead to safer pharmaceutical drugs, with reduced adverse side effects, if the methods are incorporated in clinical development. A rallying call to bring key scientists into this growing field of pharmacogenics, the application of genetics to drug... [more]
Emerging cryopreservation techniques are increasing hope of restoring fertility for women after diseases such as ovarian cancer that lead to destruction of reproductive tissue. The same techniques can also be used to maintain stocks of farm animals, and protect against extinction of endangered... [more]
The best place to seek novel compounds for pharmaceutical drugs, alternative energy sources, and a host of industrial applications, is within natural systems that have evolved over millions of years. Scientists now realise that the precise molecular arrangements within natural pathways in organisms... [more]
14 Member Organisations* of the European Science Foundation have launched a key initiative to keep Europe at the forefront of regenerative medicine; broadly defined as the development of stem cell therapies to restore lost, damaged, or ageing cells and tissues in the human body.Stem cells are the... [more]
Leading scientists today called for Europe to invest more funds into the study of lipids – the ‘fatty’ molecules that play a crucial role in the function of human cells and which are implicated in a range of diseases from obesity and diabetes to Alzheimer’s.Common lipids such as cholesterol are... [more]