Multiple Primary Tumours in Oral Cancer: aetiology and clinical significance (MPTOC)

Project Number

Convenors


Chaired by Professor Seth L. Schor
(Dental School, University of Dundee, UK)

Abstract


Oral cancer is the sixth most common cancer. ItÂ’s also a persistent disease, with a approximately 60% of patients dying from complex interactions between the environment and the human genome. The network aims to test the hypothesis that, in addition to problems in the epithelial cells that line the mouth, both inductive and carcinogen-induced alterations in stromal cell behaviour also occur during the process of field cancerisation.

Duration


Three years from January 1998 to December 2000 (extended to March 2001).