Chaired by Professor Herman Autrup
(Steno Institute of Public Health, University of Aarhus, Denmark)
Environmental toxicants play an important role in the etiology of many chronic diseases. However, there are considerable differences in individualsÂ’ susceptibility to such toxicants. Genetic polymorphisms in some of the biotransformation enzymes concerned have provided a partial explanation, but further research is needed to understand the biological consequences of those polymorphisms, the effects of which remain unknown. By bringing together laboratory-based scientists, clinicians and epidemiologists, the network aims to help better identify those groups at risk of the adverse effects of environmental toxicants.
3 years, from October 1998 to December 2001.