Two pan-European clinical trials aimed at rare diseases and paediatric population are funded under this programme:
EURAMOS, a randomised trial designed to optimize treatment strategies for patients with resectable osteosarcoma based on histological response to pre-operative chemotherapy. Osteosarcoma is the most common bone cancer in children, adolescents and young adults but it is still a rare disease with an annual incidence of 2-3 million cases per year.
EURAMOS (European and American Osteosarcoma Study Group) is a network of networks as four trial groups have joined forces to undertake this clinical trial: the Cooperative Osteosarcoma Study Group (COSS covers Austria, Germany, Hungary and Switzerland), the Scandinavian Sarcoma Group (SSG covers Denmark, Finland, Iceland, Norway and Sweden), the European Osteosarcoma Intergroup (EOI covers UK, Belgium and Netherlands) and the North American Children’s Oncology Group (COG covers USA and Canada).
A hundred and fifty clinical centres in 11 European countries (AT, BE, CH, DE, DK, FI, HU, NL, NO, SE and UK) and in USA and Canada participate in this trial; click here (pdf) to see the names of EURAMOS national coordinators. More about the EURAMOS trial.
PROFIDYS, a randomised placebo controlled trial designed to assess the safety, tolerability and efficacy of bisphosphonates in the reduction of bone pain and osteolytic lesions in patients with fibrous dysplasia of the bone. Fibrous dysplasia of the bone is a rare congenital bone disease characterized by replacement of normal bone by fibrous tissue; this disease accounts for about 2.5% of bone disorders and 7% of benign bone tumors or “pseudo-tumors”.
Clinical centres from 5 European countries (BE, DE, FR, NL and UK) participate in this trial; click here (pdf) to see the names of PROFIDYS national coordinators. More about PROFIDYS
Project Leaders
Professor Stefan Bielack (Olgahospital, Stuttgart, Germany; EURAMOS trial
Professor Philippe Orcel (Hopital Lariboisière, Paris, France; PROFIDYS trial)
Press release on the launch of EURAMOS and PROFIDYS
9 October 2007
Please click here to see the press release
Restricted web pages
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